{"id":55444,"date":"2018-05-10T06:27:54","date_gmt":"2018-05-10T05:27:54","guid":{"rendered":"https:\/\/kc.multimarketing.dev\/effet-entourage-cannabis-medical\/"},"modified":"2018-05-10T06:27:54","modified_gmt":"2018-05-10T05:27:54","slug":"effet-entourage-cannabis-medical","status":"publish","type":"post","link":"https:\/\/www.kalapa-clinic.com\/fr\/effet-entourage-cannabis-medical\/","title":{"rendered":"Qu\u2019est-ce que l’effet d\u2019entourage du cannabis m\u00e9dical?"},"content":{"rendered":"

<\/a><\/p>\n

La plupart des\u00a0<\/span>\u00e9tudes scientifiques sur le cannabis m\u00e9dical<\/span><\/a> se concentrent sur la compr\u00e9hension des effets des diff\u00e9rents types de cannabino\u00efdes, en particulier sur le THC et le CBD. Cependant, la plante de cannabis contient beaucoup plus de composants en plus des cannabino\u00efdes qu\u2019il faut prendre en compte tels que\u00a0<\/span>les terp\u00e8nes, qui ont leurs propres effets<\/span><\/a>, ou encore l\u2019effet d\u2019entourage<\/strong>.<\/span><\/p>\n

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Limiter les recherches \u00e0 un seul cannabino\u00efde r\u00e9duit l’efficacit\u00e9 de la plante<\/strong>, car ce qui se d\u00e9marque vraiment de la plante de cannabis sont les effets de plusieurs de ses \u00e9l\u00e9ments combin\u00e9s. Cependant, les r\u00e9sultats de cette combinaison diff\u00e8rent selon chaque personne. Cette interaction entre les diff\u00e9rents compos\u00e9s du cannabis est connue comme l\u2019effet d’entourage.<\/span><\/p>\n

<\/a><\/p>\n

Le manque d’information sur l’effet d\u2019entourage est ce qui a conduit le Dr Ethan Russo, \u00e0 l\u2019Universit\u00e9 du Massachusetts, \u00e0 publier\u00a0<\/span>un essai<\/span><\/a> sur la synergie des phytocannabino\u00efdes et terp\u00e8nes en 2011.<\/span><\/p>\n

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L\u2019effet d\u2019entourage pour potentialiser les effets du cannabis m\u00e9dicinal<\/b><\/h2>\n

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Plusieurs experts estiment que l’effet d’entourage est le pilier sur lequel le cannabis m\u00e9dicinal se basera \u00e0 l’avenir<\/strong>. Pourquoi en serait-il ainsi? Comme mentionn\u00e9 ci-avant, la combinaison des diff\u00e9rents \u00e9l\u00e9ments de la plante de cannabis est plus efficace que si les cannabino\u00efdes \u00e9taient isol\u00e9s<\/strong>.<\/span><\/p>\n

<\/a><\/p>\n

Selon les recherches men\u00e9es par le Dr Ethan Russo, l’un des compos\u00e9s du cannabis qui peut augmenter son potentiel est l\u2019<\/span>anandamide<\/span><\/a>. Ce compos\u00e9 simule la production \u00e0 faibles concentrations de s\u00e9bocytes qui jouent un r\u00f4le important dans de nombreuses conditions dermatologiques. Cependant, l’anandamide induit l’apoptose \u00e0 des niveaux \u00e9lev\u00e9s, ce qui signifie que les s\u00e9bocytes sont sous le contr\u00f4le du <\/span>syst\u00e8me endocannabino\u00efde<\/span><\/a>. \u00c0 cet \u00e9gard, de faibles doses de CBD n\u2019ont pas d\u2019incidence sur la synth\u00e8se de s\u00e9bocytes, mais le CBD bloque la stimulation des s\u00e9bocytes sous l\u2019anandamide et l\u2019arachidonate.<\/span>
\n<\/a><\/p>\n

L\u2019effet d\u2019entourage: terp\u00e8nes et cannabino\u00efdes combin\u00e9s<\/b><\/h3>\n

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Si l\u2019on combine les terp\u00e8nes avec les cannabino\u00efdes, les effets peuvent s\u2019av\u00e9rer d\u2019autant plus puissants<\/strong>. Deux huiles essentielles principalement compos\u00e9es de limon\u00e8ne ont montr\u00e9 efficaces pour inhiber la bact\u00e9rie <\/span>Propionibacterium acnes<\/span><\/i>, l’agent pathog\u00e8ne qui cause l’acn\u00e9, plus efficace que le triclosan. De m\u00eame, le linalool a montr\u00e9 un effet anti-inflammatoire compl\u00e9mentaire, tandis que le pin\u00e8ne est l’\u00e9l\u00e9ment le plus puissant de l’arbre \u00e0 th\u00e9 et d’eucalyptus dans la suppression des bact\u00e9ries qui produisant l’acn\u00e9.<\/span><\/p>\n

<\/a><\/p>\n

Certaines \u00e9tudes ont \u00e9galement mis l’accent sur la capacit\u00e9 de terp\u00e8nes \u00e0 combattre les infections r\u00e9sistantes \u00e0 la m\u00e9ticilline (SARM ou SARM anglais) staphylocoque. Il s\u2019agit d\u2019une souche de la bact\u00e9rie <\/span>Staphylococcus aureus<\/span><\/i> r\u00e9sistant \u00e0 divers antibiotiques. Le pin\u00e8ne a prouv\u00e9 son efficacit\u00e9 dans la lutte contre ces infections et d’autres bact\u00e9ries r\u00e9sistantes aux antibiotiques. En outre, la capacit\u00e9 des terp\u00e8nes \u00e0 am\u00e9liorer la perm\u00e9abilit\u00e9 de la peau et l’entr\u00e9e d’autres m\u00e9dicaments peut \u00eatre encore recherch\u00e9e pour des nouveaux antibiotiques.<\/span><\/p>\n

<\/a><\/p>\n

On sait maintenant que les cannabino\u00efdes sont utiles pour traiter de mani\u00e8re th\u00e9rapeutique la d\u00e9pression, l’anxi\u00e9t\u00e9, l’insomnie, la d\u00e9mence ou la d\u00e9pendance, entre autres conditions<\/strong>. Russo a \u00e9galement trait\u00e9 ces pathologies dans son \u00e9tude et a conclu que le limon\u00e8ne et le linalool pouvaient contribuer en renfor\u00e7ant les effets du CBD. De m\u00eame, ces deux terp\u00e8nes ainsi que le pin\u00e8ne peuvent collaborer pour augmenter l’effet du THC dans la d\u00e9mence des patients atteints d’Alzheimer. Le linalool, ainsi que le caryophyll\u00e8ne et le myrc\u00e8ne, peuvent augmenter les effets de plusieurs cannabino\u00efdes dans les troubles du sommeil. Enfin, le caryophyll\u00e8ne, le myrc\u00e8ne et le pin\u00e8ne peuvent \u00eatre utiles en donnant un support adjuvant dans le traitement de la toxicomanie[1]<\/a><\/span>.<\/span><\/p>\n

<\/a><\/p>\n

Parfois, il y a des pathologies qui ne peuvent \u00eatre trait\u00e9s uniquement avec un cannabino\u00efde. La synergie entre les diff\u00e9rents cannabino\u00efdes produit \u00e9galement l\u2019effet d\u2019entourage<\/strong>, un ph\u00e9nom\u00e8ne puissant dans le traitement de maladies pour lesquelles un seul composant ne saurait \u00eatre efficace. \u00c0 cet \u00e9gard, plusieurs publications font valoir que le THC contient les principaux avantages th\u00e9rapeutiques du cannabis, comme l’effet analg\u00e9sique. Cependant, d’autres \u00e9tudes confirment que le CDB et d’autres composants du cannabis r\u00e9alisent une synergie avec le THC, am\u00e9liorant ainsi de ses avantages comme antagonistes des effets ind\u00e9sirables, et produisent moins de toxicit\u00e9 qu’avec le THC seul. <\/span><\/p>\n

La gamme d’effets des phytocannabino\u00efdes est particuli\u00e8rement large ; c\u2019est la raison pour laquelle nous devons continuer d’enqu\u00eater sur son efficacit\u00e9 dans de futures applications th\u00e9rapeutiques[2]<\/a>.<\/span><\/p>\n

Un des meilleurs conseils que nous pouvons vous donner aujourd’hui pour acheter de l’huile de CBD est comparer. Comparer entre diff\u00e9rents fournisseurs, diff\u00e9rentes marques et entreprises qui en commercialisent afin de choisir la meilleure qualit\u00e9 et celle qui vous convient le mieux \u00e0 vos besoins. Pour cela, il vous sera tr\u00e8s utile d’utiliser le comparateur d’huiles de CBD<\/a>. Avec ce comparateur, vous pourrez choisir votre hile en tenant compte diff\u00e9rents facteurs comme la qualit\u00e9, la disponibilit\u00e9, les certificats, le prix et m\u00eame l’opinion des consommateurs.<\/p>\n

[1]<\/a>\u00a0Russo, E. B. (2011).\u00a0Taming THC: potential cannabis synergy and phytocannabinoid\u2010terpenoid entourage effects<\/a>.\u00a0British journal of pharmacology, 163<\/em>(7), 1344-1364.<\/p>\n

[2]<\/a>\u00a0Russo, E., & Guy, G. W. (2006).\u00a0A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol<\/a>.\u00a0Medical hypotheses, 66<\/em>(2), 234-246.<\/p>\n","protected":false},"excerpt":{"rendered":"

La plupart des\u00a0\u00e9tudes scientifiques sur le cannabis m\u00e9dical se concentrent sur la compr\u00e9hension des effets des diff\u00e9rents types de cannabino\u00efdes, en particulier sur le THC et le CBD. Cependant, la plante de cannabis contient beaucoup plus de composants en plus des cannabino\u00efdes qu\u2019il faut prendre en compte tels que\u00a0les terp\u00e8nes, qui ont leurs propres effets, […]<\/p>\n

En savoir plus \u2192<\/a><\/p>\n","protected":false},"author":32,"featured_media":51100,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[5056,3027],"tags":[4648,4716,4717,3219],"class_list":["post-55444","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cannabis-medicinal","tag-cannabis-medical","tag-effet-dentourage","tag-phytocannabinoides","tag-thc"],"yoast_head":"\nQu\u2019est-ce que l'effet d\u2019entourage du cannabis m\u00e9dical? | Kalapa Clinic<\/title>\n<meta name=\"description\" content=\"On appelle l'effet d'entourage la combinaison de diff\u00e9rents cannabino\u00efdes. 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