{"id":55407,"date":"2017-08-31T07:15:35","date_gmt":"2017-08-31T06:15:35","guid":{"rendered":"https:\/\/kc.multimarketing.dev\/quest-ce-lanandamide\/"},"modified":"2017-08-31T07:15:35","modified_gmt":"2017-08-31T06:15:35","slug":"quest-ce-lanandamide","status":"publish","type":"post","link":"https:\/\/www.kalapa-clinic.com\/fr\/quest-ce-lanandamide\/","title":{"rendered":"Qu’est-ce que l\u2019anandamide?"},"content":{"rendered":"

L\u2019anandamide est un endocannabino\u00efde qui appartient \u00e0 la classe des amides d’acides gras<\/a> [1]<\/a>. Le mot \u00ab ananda \u00bb vient du sanskrit et signifie la b\u00e9atitude, puisque c\u2019est une mol\u00e9cule qui produit du bonheur.<\/p>\n

L’anandamide interagit avec les r\u00e9cepteurs CB1 dans le syst\u00e8me nerveux et CB2 dans le syst\u00e8me nerveux p\u00e9riph\u00e9rique.<\/strong> L\u2019anandamide est \u00e9galement connu sous le nom de \u00ab la mol\u00e9cule du bonheur \u00bb, une substance produite naturellement par notre corps. Habituellement, il am\u00e9liore l’humeur lorsqu\u2019il se fixe aux neurotransmetteurs<\/a> [2]<\/a>. En outre, on peut observer des similitudes dans la structure de l’anandamide avec celle du THC, le THC \u00e9tant un cannabino\u00efde avec des vertus th\u00e9rapeutiques<\/a> qui active \u00e9galement le r\u00e9cepteur CB1.<\/p>\n

Comment l\u2019anandamide fonctionne-t\u2018il?<\/h2>\n

L\u2019anandamide peut se fixer sur les r\u00e9cepteurs cannabino\u00efdes dans notre corps bien qu’il soit une substance particuli\u00e8rement fragile qui se d\u00e9compose tr\u00e8s rapidement. L\u2019anandamide est synth\u00e9tis\u00e9 dans les zones du cerveau o\u00f9 la m\u00e9moire, la motivation, les processus cognitifs et le contr\u00f4le des mouvements sont g\u00e9r\u00e9s. Ainsi, l’anandamide influence les syst\u00e8mes physiologiques tels que la douleur, la r\u00e9gulation de l’app\u00e9tit, le plaisir et la r\u00e9compense<\/strong>. L\u2019anandamide (AEA) et les r\u00e9cepteurs CB1 ont un r\u00f4le crucial dans l\u2019ovulation, ainsi que dans l\u2019implantation du gam\u00e8te f\u00e9cond\u00e9 dans l\u2019endom\u00e8tre, ou la muqueuse ut\u00e9rine. Plus sp\u00e9cifiquement, il a \u00e9t\u00e9 d\u00e9montr\u00e9 que de hauts niveaux d\u2019anandamide sont n\u00e9cessaires pour une ovulation r\u00e9ussite et que les niveaux les plus bas sont avantageux durant l\u2019implantation du gam\u00e8te dans la muqueuse ut\u00e9rine. La m\u00eame \u00e9tude [3]<\/a> indique \u00e9galement que les niveaux d\u2019anandamide sont hauts entre la 4\u00e8 et 5\u00e8 semaine de gestation, et chutent \u00e0 des niveaux bien plus bas durant la 6\u00e8 semaine.
\nLa AEA, sous diff\u00e9rents gradients de concentration, est d\u00e9cisive pour le cycle reproductif et le bon d\u00e9veloppement f\u0153tal durant les premi\u00e8res semaines de gestation.<\/p>\n

En outre, il a \u00e9galement une influence sur la f\u00e9condit\u00e9 des femmes dans les premiers stades de la grossesse, assurant l’implantation des jeunes embryons dans la paroi de l’ut\u00e9rus.<\/p>\n

Une \u00e9tude de 2017 [4]<\/a> a v\u00e9rifi\u00e9 les effets de l\u2019anandamide sur la motivation et de r\u00e9compense<\/strong>. Confront\u00e9s \u00e0 diff\u00e9rents choix et apr\u00e8s avoir re\u00e7u une injection d\u2019anandamide, les souris ont d\u00e9montr\u00e9 qu’elles avaient une plus grande capacit\u00e9 de choisir plus rapidement ainsi qu\u2019une plus ample motivation \u00e0 choisir la meilleure solution.<\/p>\n

La relation de l’anandamide avec le cannabis m\u00e9dicinal<\/h3>\n

Comme avec le THC, l\u2019anandamide provoque un sentiment de bonheur. Jusqu’\u00e0 pr\u00e9sent, il n’a pas \u00e9t\u00e9 bien compris comment l\u2019anandamide agissait chez les animaux et sur le corps humain. Par ailleurs, apr\u00e8s avoir d\u00e9couvert le syst\u00e8me endocannabino\u00efde<\/a>, il a \u00e9t\u00e9 not\u00e9 que l’anandamide pouvait influencer et interagir avec les r\u00e9cepteurs de notre corps comme certains cannabino\u00efdes de la plante de cannabis<\/a>. De plus, plusieurs \u00e9tudes ont confirm\u00e9 leur \u00e9troite relation avec les r\u00e9cepteurs cannabino\u00efdes dans le cerveau<\/a> [5]<\/a>, bien que leurs effets psychoactifs ne soient pas encore expliqu\u00e9s.<\/p>\n

Bibliographie sur l’anandamide <\/p>\n

[1]<\/a> D. Matthew Walentiny et alt. The endogenous cannabinoid anandamide shares discriminative stimulus effects with \u22069-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. European Journal of Pharmacology Volume 656, Issues 1\u20133, 10 April 2011, Pages 63\u201367
\n[2]<\/a> J Neurochem. Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase. Vogel Z, Barg J, Levy R, Saya D, Heldman E, Mechoulam R ,1993.
\n[3]<\/a>Mona R. El-Talatini, Anthony H. Taylor, et al. \u201cFluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation.\u201d Human Reproduction, Volume 24, Issue 8, 1 August 2009, Pages 1989\u20131998, https:\/\/doi.org\/10.1093\/humrep\/dep065<\/a>
\n[4]<\/a> Pharmacology Biochemistry and Behavior, Volume 158, July 2017, Pages 14\u201321. Effects of anandamide administration on components of reward processing during free choice. Luke C. Zona, Benjamin R. Fry, Jacob A. LaLonde, Howard C. Cromwell.
\n[4]<\/a> Devane, William A., et al. \u00ab\u00a0Isolation and structure of a brain constituent that binds to the cannabinoid receptor.\u00a0\u00bb Science, vol. 258, no. 5090, 1992, p. 1946+. Academic OneFile, Accessed 26 May 2017.<\/p>\n","protected":false},"excerpt":{"rendered":"

L\u2019anandamide est un endocannabino\u00efde qui appartient \u00e0 la classe des amides d’acides gras [1]. Le mot \u00ab ananda \u00bb vient du sanskrit et signifie la b\u00e9atitude, puisque c\u2019est une mol\u00e9cule qui produit du bonheur. L’anandamide interagit avec les r\u00e9cepteurs CB1 dans le syst\u00e8me nerveux et CB2 dans le syst\u00e8me nerveux p\u00e9riph\u00e9rique. L\u2019anandamide est \u00e9galement connu […]<\/p>\n

En savoir plus \u2192<\/a><\/p>\n","protected":false},"author":23,"featured_media":18236,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[3102,5056,3027],"tags":[3676,3166,3168,4691],"class_list":["post-55407","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actualites","category-cannabis-medicinal","tag-anandamide","tag-cb1","tag-endocannabinoides","tag-systeme-endocannabinoide"],"yoast_head":"\nQu'est-ce que l\u2019anandamide?<\/title>\n<meta name=\"description\" content=\"Qu\u2019est-ce que l'anandamide et comment fonctionne-t-il? 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Copywritter focused on medical information. Searching for the last investigations of medical cannabis around the world.","url":"https:\/\/www.kalapa-clinic.com\/fr\/author\/nuria\/"}]}},"featured_image_src":"https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide.png","featured_image_src_square":"https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide.png","author_info":{"display_name":"Nuria","author_link":"https:\/\/www.kalapa-clinic.com\/fr\/author\/nuria\/"},"uagb_featured_image_src":{"full":["https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide.png",600,400,false],"thumbnail":["https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide-150x150.png",150,150,true],"medium":["https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide-300x200.png",300,200,true],"medium_large":["https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide.png",600,400,false],"large":["https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide.png",600,400,false],"1536x1536":["https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide.png",600,400,false],"2048x2048":["https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide.png",600,400,false],"gb-block-post-grid-landscape":["https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide.png",600,400,false],"gb-block-post-grid-square":["https:\/\/www.kalapa-clinic.com\/wp-content\/uploads\/2020\/10\/anandamide.png",600,400,false]},"uagb_author_info":{"display_name":"Nuria","author_link":"https:\/\/www.kalapa-clinic.com\/fr\/author\/nuria\/"},"uagb_comment_info":0,"uagb_excerpt":"L\u2019anandamide est un endocannabino\u00efde qui appartient \u00e0 la classe des amides d’acides gras [1]. Le mot \u00ab ananda \u00bb vient du sanskrit et signifie la b\u00e9atitude, puisque c\u2019est une mol\u00e9cule qui produit du bonheur. L’anandamide interagit avec les r\u00e9cepteurs CB1 dans le syst\u00e8me nerveux et CB2 dans le syst\u00e8me nerveux p\u00e9riph\u00e9rique. L\u2019anandamide est \u00e9galement connu\u2026","_links":{"self":[{"href":"https:\/\/www.kalapa-clinic.com\/fr\/wp-json\/wp\/v2\/posts\/55407","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.kalapa-clinic.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.kalapa-clinic.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.kalapa-clinic.com\/fr\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kalapa-clinic.com\/fr\/wp-json\/wp\/v2\/comments?post=55407"}],"version-history":[{"count":0,"href":"https:\/\/www.kalapa-clinic.com\/fr\/wp-json\/wp\/v2\/posts\/55407\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.kalapa-clinic.com\/fr\/wp-json\/wp\/v2\/media\/18236"}],"wp:attachment":[{"href":"https:\/\/www.kalapa-clinic.com\/fr\/wp-json\/wp\/v2\/media?parent=55407"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.kalapa-clinic.com\/fr\/wp-json\/wp\/v2\/categories?post=55407"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.kalapa-clinic.com\/fr\/wp-json\/wp\/v2\/tags?post=55407"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}