THCA (tetrahydrocannabinolic acid) is the non-psychoactive form of THC, which can convert to THC when it is decarboxylated. There are many researches which investigate the medical effectiveness of THCA on diseases like epilepsy, chronical pain, digestive disorders and many more.
Tetrahydrocannabinolic acidcan only be found in a fresh undried Cannabis plant, because once the plant is dried or heated the THCA decays. Its medical effectiveness has been proven multiple times.
But how does it work and with which components does it interact? There haven’t been a lot of studies about with which receptors THCa interacts, however it can be said that it has effects on different once, which are for example responsible for different kind of tastings. Most interesting is the possibility that it might inhibit the metabolic enzyme MAGL. This enzyme breaks down the endogenous cannabinoid 2-AG and would result in higher levels of 2-AG, which are activating the CB1 and CB2 cannabinoid receptors throughout the whole body. This would lead to an overall proven therapeutic effect on multiple conditions.
THCa and its effects
Dustin Sulak, Russal Saneto and Bonni Goldstein have done some research on the effectiveness of THCa and had some promising results on the treatment of epilepsy. Along with other medication THCa helped to be overall more effective on man patients.
Besides epilepsy it also has been shown that tetrahydrocannabinolic acid can be affective in the treatment of Alzheimer, also along with other medication. Patients could restore cognitive activities and experienced a noticeable improvement. Furthermore, preliminary research and anecdotal evidence have unveiled that cannabinoid has potential benefits on: Anti-inflammatory properties for treatment of arthritis and lupus; neuroprotective properties for treatment of neurodegenerative diseases; anti-proliferative properties noted in studies of cancer.
However, the studies must be continued, because until now there has not been done a fully scientifically medical trial with THCa to prove if and in which combination that cannabinoid can heal or help multiple diseases.