Anandamide – this endocannabinoid makes us happy

“Bliss” – this is the meaning of anandamide, the best known and scientifically first described endocannabinoid. It is one of the most important endocannabinoids for controlling the balance in our body, called homeostasis. Humans – but also other mammals and insects – produce endogenous cannabinoids, so-called endocannabinoids. These activate the body’s endocannabinoid system (ECS), just […]

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Cancer and Cannabis: the state of pre-clinical research

Cannabinoids are already used for cancerous diseases to relieve symptoms such as pain, vomiting from chemotherapy and anorexia. Preclinical studies on animals and cultures of cancer cells increasingly show that cannabinoids have an anticarcinogenic effect, therefore, they also fight cancer. The endocannabinoid system (ECS) is involved in tumor defense, from which therapeutic effects for phytocannabinoids […]

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Cannabis for sleep disorders

The endocannabinoid system (ECS) controls many bodily functions such as pain perception, memory, and sleep. An analysis by Canadian researchers of 24,189 user data from the cannabis app Strainprint showed significant relief from insomnia. Discomfort decreased by more than half. Indica-dominant cannabis strains, which contain mainly psychotropic tetrahydrocannabinol (THC), were preferred. Sleep disorders – widespread […]

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Ulcerative colitis and medicinal cannabis

Many studies point to the medical potential of the cannabis plant. Among other things, its ingredients are said to have a pain-relieving and anti-inflammatory effect, which could be beneficial in the chronic disease ulcerative colitis. Like Crohn’s disease, ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD). While ulcerative colitis only inflames the rectum […]

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Multiple sclerosis: treatment with medical cannabis

Multiple Sclerosis (MS) usually occurs between the ages of 20 and 40. The neurological disease progresses episodically, and symptoms may vary. While standard therapies can reduce the frequency and duration of relapses, drug therapies are not free of severe side effects. Medical cannabis provides a complementary therapy option low on side effects, to alleviate various […]

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Cannabis-based medicines have best benefit-safety profile

An international team of researchers compared three cannabinoid therapies with six non-cannabis-based medicines. The drugs were assessed according to their risk-benefit ratio for the treatment of chronic nerve pain in adults. The result: although cannabinoids are inferior to the drugs amitriptyline, duloxetine and gabapentin in terms of pain relief, cannabis-based drugs improve quality of life […]

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Flavonoids in cannabis

Cannabis is mostly associated with phytocannabinoids such as the psychotropic tetrahydrocannabinol (THC). Research shows that other constituents – terpenes and flavonoids – influence the therapeutic effect, which is called the entourage effect. Although the coloured flavonoids are widespread in the plant kingdom, little is known about their medicinal effects. Here we explain what these plant […]

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Side effects of cannabinoids

Like other medicines, medicinal cannabis can cause side effects. These are mainly triggered by the active substance tetrahydrocannabinol (THC), the most important psychotropic cannabinoid. The non-intoxicating cannabidiol (CBD) is considered to be well tolerated, but can also produce undesirable effects. Compared to many other medicines, cannabis is well tolerated: If the prescribing doctor takes into […]

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Survey: Cannabis for breast cancer

Therapeutic advances in recent years have increased the chances of curing breast cancer. However, cancer drugs can cause severe side effects such as pain, nausea and anorexia (loss of appetite). This not only affects the quality of life. The success of the therapy is also at risk, as some people stop taking the cancer drugs […]

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