Cannabinoids and Mixed Syndromes

There are several clinical studies that have demonstrated the effectiveness of the medical use of cannabinoids for diseases such as epilepsy, multiple sclerosis, cancer, etc. Cannabinoids have also shown a number of good results in medical cases which are more difficult to classify, such as hypo-Parkinson.

The therapeutic effects of cannabinoids have also shown positive results in other diseases that fall within the therapeutic spectrum of THC. An example of this would be diseases with an inflammatory origin, such as arthritis. Also in diseases that cause muscle spasms, such as menstrual cramps and spinal cord injuries. Finally, the effect of cannabinoids have demonstrated positive effects on diseases that relate to nausea, anorexia, pain, episodes of anxiety and even depression.

Mixed Syndromes

  • Cannabinoids Decrease Pain Reactivity
  • Activation of descending inhibitory system pathways
  • Treatment for oncological pain
  • Treatment for neuropathic pain
  • Treatment of Post-Operative pain


The analgesic effect of cannabinoids is one of the best characterized effects. The results of the studies suggest that cannabinoids may offer some benefit as an additional treatment for cancer pain and neuropathic pain.

Cannabinoid treatments for mixed syndromes.

Arthritis is an inflammatory disease that affects the joints and is characterized, by symptoms such as pain, stiffness and swelling. Several scientific studies have demonstrated the therapeutic effect of cannabinoids for arthritis. A study executed by researchers at the National Institute of Neuroscience in Tokyo concluded that by treating arthritis with cannabinoids they could “provide symptomatic relief of joint pain and inflammation as well as suppress joint destruction and disease progression.” [1] In the same string of research the Royal British National Hospital conducted a controlled study on the treatment of arthritis with cannabinoids which produced very promising results.[2]

Thousands of women suffer from colic, muscle spasms or endometriosis during menstruation. Several studies have shown that cannabinoids can relieve the symptoms of endometriosis (pain, anxiety, fatigue …). In addition, research indicates that CBD can reduce inflammation in these cases allowing women to control their pain during menstruation [3].

Another case in which cannabinoids have been shown to have an effect, is in spinal cord injuries. There have been studies which confirm the relief that medical cannabis can bring to spinal cord injury sufferers. In particular CBD has been shown to reduce spasticity in patients with spinal cord injury and to improve general motor skills. THC can also help to improve other symptoms of this disease such as pain or insomnia.

Bibliography for Mixed Syndromes and Cannabinoids

[1] CROXFORD AND YAMAMURA.  2005. Cannabinoids and the immune system: potential for the treatment of inflammatory diseases. Journal of Neuroimmunology 166: 3-18.

[2] BLAKE ET AL. 2006. Preliminary assessment of the efficacy, tolerability and safety of a cannabis medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology 45: 50-52.

[3] MIRANDA. 2015. Cannabis y endometriosis, la enfermedad del silencio

Use cannabinoids for
Mixed Syndromes




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