The legal status of the cannabis plant has made it difficult for studies and investigations to demonstrate its beneficial properties to treat many pathologies. This has led to a lack of scientific review on the efficiency of cannabinoid therapy for cannabinoid use compared to other modes of consumption of the Cannabis Sativa L plant. For this reason, a group of experts at an institutional level developed a consensus regarding medical cannabis-based therapies .
The paper aimed to review the most relevant scientific information about the therapeutic use of cannabinoids, such as THC or CBD. In addition, the publication reviews the most important data about the endocannabinoid system in relation to human diseases in order to reflect present and future uses of medical cannabis therapies. After a brief historical introduction and a presentation on what the endocannabinoid system is and the functions that have been discovered so far, the study compares the effects of herbal cannabis with those of plant-based drugs.
“The endocannabinoid system is very complex in functioning and distribution: we know the distribution of the receptors, we are aware of the mechanisms of the molecular action and we think that many diseases or pathologies are a consequence of a malfunction of our endocannabinoid system”, explains Dr. Mariano García de Palau a cannabinoid specialist at Kalapa Clinic. Experts are optimistic and have indicated that future research will focus on identifying the link between this system and specific pathologies. The researchers believe that the introduction of new agents directed to specific objectives within the endocannabinoid system.
Information about medical cannabis-based therapies
Consensus experts have pointed out that there are some misconceptions among society, and even among healthcare professionals about the use of cannabinoid based drugs. Experts believe that the benefits of these drugs should be emphasize when used as a monotherapy, as many patients are choosing to use only cannabinoid-based products to treat their medical conditions.
 Maccarrone, M., Maldonado, R., Casas, M., Henze, T., & Centonze, D. (2017). Cannabinoids therapeutic use: what is our current understanding following the introduction of THC, THC: CBD oromucosal spray and others?. Expert Review of Clinical Pharmacology, 10(4), 443-455.